Materia Medica: Passionflower

Passionflower

(Passiflower incarnata)

Common Names: Maypop, Passion Vine, Purple Passionflower

Family: Passifloraceae 

Parts Used: Leaf, Whole plant

Herbal Actions: Nervine, Hypnotic, antispasmodic, anodyne, hypotensive

Health Benefits: Used to calm and soothe, it is used as a sleep aid that does not leave one feeling groggy the following morning. It is hypotensive and acts as a CNS depressant. Antispasmodic and anti-inflammatory effects are known to be caused by flavonoids in passionflower. Passionflower may be helpful for neuralgia, shingles and nerve related pain.

Historical Use:  

• Passionflower has a long history of use in both the Americas and Europe as a natural remedy for anxiety and insomnia. Traditionally employed to address conditions like seizures and hysteria, it continues to be valued today for its calming properties. Scientists attribute its effectiveness to its ability to elevate GABA levels in the brain, a neurotransmitter that promotes relaxation and reduces nervous activity.

Research & Clinical Studies:

• Improved Sleep Quality: Some research indicates that passionflower can improve sleep quality, especially in individuals with mild to moderate insomnia.

• Reduced Stress: Animal studies have shown that passionflower may help reduce stress levels and improve cognitive function.

Active Constituents:

• Flavonoids (apigenin, homoorientin, isovitexin, kaemferol, luteolin, vitexin, orientin, quercetin, rutin, saponaretin, saponarin)

• Alkaloids (harman, harmine, harmol, harmaline, harmalol, passaflorine,)

Safety & Precautions:

• Generally safe 

• May interact with certain medications, including sedatives and antidepressants.

• Considered to be contraindicated for those taking MAOI medications

• Consult with a healthcare professional before using skullcap, especially if pregnant, breastfeeding, or taking other medications.